Process Planning

The company Dr. Franz Köhler Chemie GmbH located in Bensheim is specialised in the production of organ protective dilutions, therapeutics, X-ray contrast agent, vascular protection dilutions and antidotes. The production of liquid drugs is carried out at the Bensheim site. During a reorganization the Alsbach site was restructured into a research centre.

Project challenges

To satisfy the increasing global demand of their products, Dr. Franz Köhler Chemie builts a new facility at their Bensheim site for the production of CUSTODIOL®. In addition an analytical laboratory was built for quality control, on-site testing and release. The focus was on national and international GMP requirements. The new production site with an overall area of 1.750 m² (class C and D cleanrooms) includes the following functional areas: Media supply, weighing area, compounding, filling, terminal sterilization, autoclaving, cooling, packaging and warehousing.

The infusion bags with volumes of 100 to 5.000 ml are filled and sealed in a modern fill/finish system and sterilized by a hot water cascade.

Task: 
Process planning for new production facility from concept planning to qualification

Services:
Pharma/Biotech planning

Location:
Bensheim, Germany

Customer value

io-consultants acted as a process planer to generate an optimal concept for the production and to meet the technological standards of the client. The tasks include all phases from concept design to realization and qualification.

A professional control of interfaces between subcontractors, architects including MEP and process contributed to the success of the project. Consistent implementation of lean manufacturing concepts lead to an efficient material flow and optimized process.

Please contact us 

Dr. Gregor Dudziak Member of the Management Board/Partner Phone: +49 (0) 62 21 / 379-111